Job Description

Are you an experienced Biochemist - High-Throughput Screening with a desire to excel? If so, then Talent Software Services may have the job for you! Our client is seeking an experienced Biochemist - High-Throughput Screening to work at their company in Rahway, NJ.

Primary Responsibilities/Accountabilities: The Chemical Biotechnologies Group at the client is seeking an experienced researcher to support our high-throughput capabilities.

• The mission of the group is to invent, develop, and implement biomolecules and biocatalytic processes to advance the client’s pipeline and our impact on the scientific community.
• This position in our biochemistry team is responsible for lysing E. coli cell pellets to liberate enzyme in solution or generate enzyme from in vitro transcription translation (ivTT) mix, setting up reactions using this solution as a catalyst solution, quenching reactions and prep them for HPLC analysis, running the HPLC, and analyzing the data generated in support of our protein directed evolution workflow.
• The candidate will perform high throughput workflows with 96 or 384 well formats using various automation instruments.
• The candidate will have hands-on, extensive experience with instrumentation essential for monitoring substrates and products profiles for reactions, especially Agilent UPLC systems.
• In this position, the candidate will have the opportunity to work with a diverse group of team members to effectively coordinate efforts and operate multiple projects.
• The candidate ensures activities of assignments are executed such that project deliverables and timelines are met.
• The candidate is responsible for good housekeeping and performing work in a safe manner in the work area by applicable safety equipment and personnel protective equipment (PPE).

Qualifications:

• Bachelor's degree in Molecular Biology, Synthetic Biology, Bioengineering, Biochemistry or related field with +5 years’ of experience, or MS with +2 years of experience, or PhD.
• Experienced in high-throughput screening and automated liquid handling (Biomek or Tecan liquid handling systems) and various analytical methods (HPLC, LC-MS, spectrophotometry, gel electrophoresis, FPLC).
• Proficient in preparing chemical and biochemical reactions
• Experience with protein handling and biochemical, biophysical, and/or phenotypic protein characterization techniques (e.g., activity assays, SDS-PAGE, UV-Vis spectrophotometry).
• Understanding of experimental design and data analysis principles
• Strong organizational skills and attention to detail
• Excellent teamwork and multitasking
• Good documentation of experimental reports
• Software Skills: MS office (Word/Excel)

Preferred:

• Experience with one or more of the following: next-generation sequencing, directed evolution, protein expression or microfluidics
• Experience in protein characterization and purification
• Experience in protein expression platforms (yeast, bacillus, mammalian) is a plus
• Experience with data analysis using Python, R, Excel, or similar tools
• Industry experience is preferred.

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